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| The Effect of Ethanol Infusion on the Size of the Ablated Lesion in Radiofrequency Thermal Ablation: A Pilot Study |
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| Young-Sun Kim Young-Sun Kim, M.D., Hyunchul Rhim, M.D., Byung Hee Koh, M.D.,On Koo Cho, M.D., Heung Suk Seo, M.D., Yongsoo Kim, M.D.,Kyoung Bin Joo, M.D. |
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| Department of Diagnostic Radiology, College of Medicine, Hanyang University |
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| PURPOSE : To assess the effect of ethanol infusion on the size of ablated lesion during radiofrequency (RF) thermal
ablation.
MATERIALS and METHODS : We performed an ex vivo experimental study using a total of 15 pig livers. Three groups
were designed; 1) normal control (n=10), 2) saline infusion (n=10), 3) ethanol infusion (n=10). Two radiofrequency
ablations were done using a 50 watt RF generator and a 15 guage expandable electrodes with four
prongs in each liver. During ablation for 8 minutes, continuous infusion of fluid at a rate of 0.5 ml/min through
the side arm of electrode was performed. We checked the frequency of the “impeded-out” phenomenon due to
abrupt increase of impedance during ablation. Size of ablated lesion was measured according to length, width,
height, and subsequently volume after the ablations. The sizes of the ablated lesions were compared between the
three groups.
RESULTS : “Impeded-out” phenomenon during ablation was noted 4 times in control group, although that has never
happened in saline or ethanol infusion groups. There were significant differences in the volumes of ablated lesions
between control group (10.62±1.45 cm3) and saline infusion group (15.33±2.47 cm3), and saline infusion
group and ethanol infusion group (18.78±3.58 cm3) (p<0.05).
CONCLUSION : Fluid infusion during radiofrequency thermal ablation decreases a chance of charring and increase
the volume of the ablated lesion. Ethanol infusion during ablation may induce larger volume of ablated lesion
than saline infusion. |
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| Keyword : Liver, interventional procedure, Interventional procedures, experimental, Liver neoplasms, therapy |
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pdf파일 : k20200175.pdf 
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> Journal > Journal Search 
Journal of Korean Society of Ultrasound in Medicine 2001 ; 20 (3) : p.175 - 180
